|Congressman Barney Frank and challenger Sean Bielat|
"If Barney Frank loses, it would be as significant as Scott Brown's win. You would really begin to see the depths of this anti-government sentiment," said Marc Landy, professor of political science at Boston College.
Massachusetts has already been the scene of one of the year's biggest upsets, when Republican Scott Brown won a special election for the U.S. Senate seat held for almost five decades by a Democratic Party pillar, the late Edward Kennedy.
A recent opinion poll showed Frank with 49 percent of likely voters, Sean Bielat at 37 percent and 12 percent undecided. Frank kept his seat in the House of Representatives with 68 percent of the vote in 2008 and ran unopposed in 2006.
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